靶标９�p style="text-indent: 2em;">TLX1

产品别名９�p style="text-indent: 2em;">HOX11� TCL3� TLX1� T cell leukemia homeobox 1� T cell leukemia homeobox 1� T-cell leukemia homeobox protein 1� T-cell leukemia/lymphoma protein 3� homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to Drosophila Notch)� homeobox protein Hox-11� proto-oncogene TCL-3� T细胞白血病淋巴瘤蛋白3�

背景信息９�div style="text-indent: 2em;">This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010],