靶标９�p style="text-indent: 2em;">GUCY2D

产品别名９�p style="text-indent: 2em;">CACD1� CG-E� CORD5� CORD6� CSNB1I� CYGD� GUC1A4� GUC2D� LCA� LCA1� RCD2� RETGC-1� ROS-GC1� ROSGC� retGC� GUCY2D� guanylate cyclase 2D, retinal� guanylate cyclase 2D, retinal� retinal guanylyl cyclase 1� ROS-GC� cone rod dystrophy 6� guanylate cyclase 2D, membrane (retina-specific)� retinal guanylate cyclase 1� rod outer segment membrane guanylate cyclase�

背景信息９�div style="text-indent: 2em;">This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.