靶标９�p style="text-indent: 2em;">GOLGB1

产品别名９�p style="text-indent: 2em;">GCP� GCP372� GOLIM1� GOLGB1� golgin B1� golgin B1� golgin subfamily B member 1� 372 kDa Golgi complex-associated protein� giantin� golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1� golgi integral membrane protein 1� golgin B1, golgi integral membrane protein� 高尔基体相关蛋白GCP372�

背景信息９�div style="text-indent: 2em;">Giantin or Golgin subfamily B member 1 is a protein that in humans is encoded by the GOLGB1 gene. GOLGB1, also known as Giantin and Macrogolgin, is a 360 to 400 kDa member of the Golgin protein family. GOLGB1 is an integral component of the Golgi membrane that associates with the cytoskeleton. It may be involved in both forming intercisternal cross-bridges that mediate stacking in Golgi complexes, and in reorganizing the complexes after they fragment during mitosis. GOLGB1 has also been identified as an autoantigen in chronic rheumatoid arthritis, and in the autoimmune disease Sjoegren syndrome. Human GOLGB1 is 3259 amino acids (aa) in length, and over aa 1596-1702, shares 92% and 91% sequence identity with its mouse and rat orthologs, respectively.