靶标９�p style="text-indent: 2em;">EVPL

产品别名９�p style="text-indent: 2em;">EVPK� EVPL� envoplakin� envoplakin� envoplakin� 210 kDa cornified envelope precursor protein� 210 kDa paraneoplastic pemphigus antigen� 外皮蛋白(EVPL)�

背景信息９�div style="text-indent: 2em;">This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein.