靶标９�p style="text-indent: 2em;">COL15A1

产品别名９�p style="text-indent: 2em;">COL15A1� collagen type XV alpha 1 chain� collagen type XV alpha 1 chain� collagen alpha-1(XV) chain� collagen XV, alpha-1 polypeptide� collagen type XV proteoglycan� collagen, type XV, alpha 1� endostatin-XV� restin�

背景信息９�div style="text-indent: 2em;">This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration.