靶标９�p style="text-indent: 2em;">CHRND

产品别名９�p style="text-indent: 2em;">ACHRD� CMS2A� CMS3A� CMS3B� CMS3C� FCCMS� SCCMS� CHRND� cholinergic receptor nicotinic delta subunit� cholinergic receptor nicotinic delta subunit� acetylcholine receptor subunit delta� acetylcholine receptor, nicotinic, delta (muscle)� cholinergic receptor, nicotinic delta� cholinergic receptor, nicotinic, delta (muscle)� cholinergic receptor, nicotinic, delta polypeptide� 烟碱型乙酰胆碱受体�?AChRδ�

背景信息９�div style="text-indent: 2em;">The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.