靶标９�p style="text-indent: 2em;">CACNA1A

产品别名９�p style="text-indent: 2em;">APCA� BI� CACNL1A4� CAV2.1� DEE42� EA2� EIEE42� FHM� HPCA� MHP� MHP1� SCA6� CACNA1A� calcium voltage-gated channel subunit alpha1 A� calcium voltage-gated channel subunit alpha1 A� voltage-dependent P/Q-type calcium channel subunit alpha-1A� brain calcium channel 1� brain calcium channel I� calcium channel, L type, alpha-1 polypeptide� calcium channel, voltage-dependent, P/Q type, alpha 1A subunit� fetal brain Ca2+ voltage-gated channel alpha1A pore-forming subunit� voltage-gated calcium channel subunit alpha Cav2.1� 电压依赖性钙通道Cav2.1�

背景信息９�div style="text-indent: 2em;">calcium voltage-gated channel subunit alpha1 A(CACNA1A) Homo sapiens Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits