靶标９�p style="text-indent: 2em;">SHROOM2

产品别名９�p style="text-indent: 2em;">APXL� HSAPXL� SHROOM2� shroom family member 2� shroom family member 2� protein Shroom2� APX homolog of Xenopus� apical-like protein� APXL蛋白�

背景信息９�div style="text-indent: 2em;">Shroom family member 2 is a protein that in humans is encoded by the SHROOM2 gene. This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene.