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蛋白质/抗原/多肽 >> 重组蛋白
重组NFKB激活蛋白
重组NFKB激活蛋白图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: 重组NFKB激活蛋白(NKAP)
Recombinant Nkap
半岛bd体育手机客户端 介绍
基因名:

Nkap


半岛bd体育手机客户端 别名:

2610020O08Rik; AA987160; AI849147; AL024236; Nkap; NFKB activating protein; NFKB activating protein; NF-kappa-B-activating protein; nuclear NF-kappaB activating protein; NFKB激活蛋白; NFKB激活蛋白(NKAP);


背景信息:
NFκB, a pleiotropic transcription factor, is present in almost all cell types and is involved in many biological processes including inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFκB is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFκB1/p105, NFκB1/p50, REL and NFκB2/p52. This complex is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NKAP (NF-κ-B-activating protein) is a 415 amino acid nuclear protein that regulates TNF and IL1-induced NFκB activation. As component of a DNA-binding complex, NKAP also functions as a transcriptional repressor that acts on NOTCH target genes. Loss of NKAP blocks the development of αβT- cells, suggesting that it is required for their maturation through repression of NOTCH genes.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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