半岛bd体育手机客户端 介绍
基因名：
ST8SIA1 半岛bd体育手机客户端 别名： GD3S； SIAT8； SIAT8-A； SIAT8A； ST8SiaI； ST8SIA1； ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1； ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1； alpha-N-acetylneuraminide alpha-2,8-sialyltransferase； ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 1； alpha-2,8-sialyltransferase 8A； disialoganglioside (GD3) synthase； ganglioside GD3 synthase； ganglioside GT3 synthase； ganglioside-specific alpha-2,8-polysialyltransferase； sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3 synthase) A； sialyltransferase 8A (alpha-N-acetylneuraminate: alpha-2,8-sialyltransferase, GD3 synthase)； sialyltransferase St8Sia I； sialytransferase St8Sia I； 背景信息：
α-N-Acetylneuraminide α-2,8-Sialyltransferase (ST8SIA1) belongs to the glycosyltransferase 29 family. ST8SIA1 is a sialytransferase that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce GD3 and GT3. ST8SIA1 is highly expressed in melanoma cell lines, adult and fetal brain, low expressed in adult and fetal lung. ST8SIA1 may act as a type II transmembrane protein with a short N-termianl cytoplasmic domain and a single-pass transmembrane domain folowed by an enzymatic domain in the lument of the Golgi apparatus.
标签：His-tag |
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