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蛋白质/抗原/多肽 >> 重组蛋白
重组O-岩藻糖肽3-β-N-乙酰氨基葡萄糖转移酶(RFNG)蛋白
重组O-岩藻糖肽3-β-N-乙酰氨基葡萄糖转移酶(RFNG)蛋白图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: 重组β1,3-N-乙酰糖基转移酶蛋白
Recombinant RFNG
半岛bd体育手机客户端 介绍
基因名:

RFNG


半岛bd体育手机客户端 别名:

RFNG; RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; beta-1,3-N-acetylglucosaminyltransferase radical fringe; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; radical fringe homolog; O-岩藻糖肽3-β-N-乙酰氨基葡萄糖转移酶(RFNG); β1,3-N-乙酰糖基转移酶;


背景信息:
Three mammalian fringe family members, Manic, Radical and Lunatic Fringe, have been identified as proteins related to Drosophila Fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian Fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Radical Fringe, also known as Beta-1,3-N-acetylglucosaminyltransferase Radical Fringe, is a 331 amino acid single-pass type II membrane protein that localizes to the membrane of the Golgi apparatus. Playing a key role in the development of the limb bud, Radical Fringe transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor. Lunatic Fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock. Manic Fringe, also involved in somatic development, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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