半岛bd体育手机客户端 介绍
基因名：
CYP2C18 半岛bd体育手机客户端 别名： CPCI； CYP2C； CYP2C17； P450-6B/29C； P450IIC17； CYP2C18； cytochrome P450 family 2 subfamily C member 18； cytochrome P450 family 2 subfamily C member 18； cytochrome P450 2C18； (S)-mephenytoin hydroxylase associated cytochrome P450； CYPIIC18； cytochrome P450, family 2, subfamily C, polypeptide 18； cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17； cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18； cytochrome P450-6B/29C； flavoprotein-linked monooxygenase； microsomal monooxygenase； unspecific monooxygenase； 细胞色素P450 2C18； 背景信息：
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
标签：His-tag |
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