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异亮氨酰tRNA合成酶(IARS)抗体
半岛bd体育手机客户端 介绍
靶标:
IARS1 半岛bd体育手机客户端 别名: GRIDHH; IARS; ILERS; ILRS; IRS; PRO0785; IARS1; isoleucyl-tRNA synthetase 1; isoleucyl-tRNA synthetase 1; isoleucine--tRNA ligase, cytoplasmic; isoleucine tRNA ligase 1, cytoplasmic; 异亮氨酰tRNA合成酶(IARS); 背景信息:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.
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