抗体 >> 其他抗体
组织相容性复合体α抗体
半岛bd体育手机客户端 介绍
靶标：
HLA-DMA 半岛bd体育手机客户端 别名： D6S222E； DMA； HLADM； RING6； HLA-DMA； major histocompatibility complex, class II, DM alpha； major histocompatibility complex, class II, DM alpha； HLA class II histocompatibility antigen, DM alpha chain； MHC class II antigen DMA； class II histocompatibility antigen, M alpha chain； really interesting new gene 6 protein； 组织相容性复合体α； 背景信息：
HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.
宿主：Rbt |
相关半岛bd体育手机客户端
|
